Suboxone vs. Methadone: Understanding the Treatments for Opioid Use Disorder

Suboxone vs. Methadone

Suboxone vs. Methadone

Opioid addiction is a complex and challenging condition, but evidence-based treatments like Suboxone and Methadone have revolutionized recovery. Both medications are part of Medication-Assisted Treatment (MAT), a holistic approach combining medications with behavioral therapy.

While both Suboxone and Methadone are effective, they differ in their mechanisms, accessibility, and overall benefits. Understanding these differences is crucial for choosing the proper treatment for long-term recovery.

What Are Suboxone and Methadone?

  • Suboxone is a combination medication containing buprenorphine (a partial opioid agonist) and naloxone (an opioid antagonist). Buprenorphine activates opioid receptors in the brain to reduce withdrawal symptoms and cravings, but only partially, limiting the risk of misuse. Naloxone is included as a deterrent to injection misuse, as it can trigger withdrawal symptoms if injected.
  • Methadone, on the other hand, is a full opioid agonist that binds to opioid receptors to relieve cravings and withdrawal symptoms without causing the euphoric high associated with heroin or other opioids. Methadone has been used for decades as a gold standard in opioid addiction treatment.

Benefits of Suboxone

Suboxone offers several advantages, particularly for individuals seeking flexibility and safety in their recovery journey.

  1. Lower Risk of Overdose
    Suboxone’s partial agonist properties mean there’s a ceiling effect on its opioid activity. This reduces the risk of respiratory depression and overdose compared to Methadone, making it a safer option for many patients.
  2. Ease of Access and Flexibility
    Unlike Methadone, which typically requires daily visits to specialized clinics, Suboxone can be prescribed by certified healthcare providers and taken at home. This makes it more accessible for patients who may have transportation barriers or busy schedules.
  3. Deterrent to Misuse
    The inclusion of naloxone in Suboxone reduces the potential for misuse. If someone attempts to inject Suboxone, the naloxone component will trigger withdrawal symptoms, discouraging abuse.
  4. Reduced Stigma
    Because Suboxone can be prescribed in a regular doctor’s office, it often feels less stigmatizing than visiting a Methadone clinic. For many, this discretion and privacy enhance their commitment to treatment.
  5. Milder Side Effects
    Suboxone is associated with fewer side effects compared to Methadone, particularly in terms of sedation. This allows patients to maintain a higher level of functioning during treatment.
  6. Convenience for Long-Term Maintenance
    Suboxone is ideal for long-term maintenance therapy, especially for patients who are stable and ready to manage their recovery more independently.

Benefits of Methadone

Methadone has been a cornerstone of opioid addiction treatment for decades, offering unique benefits for certain populations.

  1. High Efficacy for Severe Addiction
    Methadone’s full agonist properties make it highly effective for individuals with severe opioid addiction or those who have not responded well to other treatments.
  2. Long History of Use
    Methadone has a well-documented track record, with extensive research supporting its efficacy. It has been shown to reduce opioid use, improve retention in treatment, and lower rates of overdose deaths.
  3. Controlled Dosing in Clinical Settings
    Methadone is typically administered in specialized clinics, where dosing is carefully monitored. This structure is beneficial for individuals who need a highly controlled environment to support their recovery.
  4. Affordability
    Methadone is often more affordable than Suboxone, particularly for patients without insurance. Many clinics also offer sliding-scale payment options, making Methadone accessible to underserved populations. Patients are more likely to find a free methadone clinic than a free Suboxone clinic in Tennessee.
  5. Supportive Environment
    Methadone clinics often provide additional resources, such as counseling, support groups, and case management services, creating a comprehensive recovery environment.

Key Differences: Suboxone vs. Methadone

While both medications are effective for opioid addiction treatment, their differences can influence a patient’s decision:

Feature

Mechanism:

Risk of Overdose:

Accessibility:

Potential for Misuse:

Cost:

Efficacy for Severe Cases:

Drug Interactions:

Suboxone

Partial agonist (with naloxone)

Lower

Prescribed in-office; at-home use

Low (due to naloxone)

Higher without insurance

May be less effective

Reacts well to other medications

Methadone

Full agonist

Higher

Requires daily visits to a clinic

Higher risk

May be more affordable

Highly effective for severe addiction

Reacts poorly with other medications

Additional Benefits: Suboxone’s High Accessibility

Recovery can feel great when you first begin due to feeling light years better than you did when abusing drugs. However, you'll eventually need practicality to protect your long-term sobriety. When considering Suboxone vs. Methadone, it's essential to consider conveniences like medication availability and accessibility, appointment times and frequency, and more. Your recovery is critical to your quality of life. Make sure you choose a recovery program that will work for you long-term.

  • Available at Local Pharmacies
    Suboxone has become the staple for medication-assisted treatment due to its low risk of misuse. Suboxone prescriptions can be prescribed to patients at their first telemedicine appointment and picked up at their local pharmacy. 
  • Suboxone Delivered to Your Home
    Nashville Addiction Clinic has partnered with a special pharmacy that will ship Suboxone medications to your home. An overnight delivery fee is required.
  1. Phases of Treatment
    Suboxone is prescribed as part of a medication-assisted treatment (MAT) program. MAT contains phases of treatment in which patients gain more freedom and attend less frequent appointments over time.

    1. Induction - The first visit is used to transition from prescription pain pills or illicit substances to the safer Suboxone.
    2. Stabilization - Four weekly visits that follow Induction. Patients are monitored, a recovery plan is established, and patients are monitored for correct dosages.
    3. Maintenance 1 - Four biweekly visits following stabilization. 
    4. Maintenance 2 - Monthly visits that follow Maintenance 1. 

How to Choose Between Suboxone and Methadone

The decision between Suboxone and Methadone depends on several factors, including the severity of addiction, lifestyle, and personal preferences.

  • Suboxone is better suited for individuals with mild to moderate opioid addiction or those who prioritize flexibility and privacy in their treatment. Its safety profile makes it a preferred option for patients at risk of overdose. Patients can quickly gain more freedom and attend less-frequent visits thanks to the phases of treatment noted above.
  • Methadone is ideal for individuals with severe addiction or those who benefit from the structure and accountability of clinic-based treatment. It’s also a strong choice for patients who have tried other treatments without success. Daily visits are very likely, though some patients may advance to less-frequent visits over time.

Conclusion

Both Suboxone and Methadone are life-saving tools in the fight against opioid addiction, but their unique benefits cater to different needs. Suboxone offers flexibility, safety, and privacy, making it an excellent choice for many. Methadone, with its high efficacy and structured clinical setting, remains a cornerstone of treatment for severe cases.

Ultimately, the best choice depends on individual circumstances, preferences, and medical advice. Whichever option you choose, seeking professional help and committing to a comprehensive recovery plan is the first step toward reclaiming your life from addiction.

Switching from Methadone to Suboxone

Keep in mind: Some people choose to switch from Methadone to Suboxone. While methadone may be needed for the initial stages of your recovery, it's very possible to reduce your methadone dosage gradually over time (known as a "taper") and switch to Suboxone. This should only be done while under the care of a trained medical professional who is familiar with transitioning patients from Methadone to Suboxone.

Nashville Addiction Clinic: The Suboxone Clinic for All of Tennessee Accepting All Major Insurance and TennCare Medicaid

Nashville Addiction Clinic provides a state-of-the-art, telemedicine-based, outpatient addiction treatment program using Suboxone medications, therapy, and case management. Here are some other benefits that make Nashville Addiction Clinic a great choice for anyone struggling with opioid use disorder:

  • Tennessee’s Very First Virtual OBOT Medical License
    NAC was honored to receive Tennessee’s first “virtual” office-based outpatient treatment medical license. This coveted medical license allows NAC to provide telemedicine addiction treatment to anyone living in Tennessee.
  • A TennCare BeSMART Provider
    Only the top-performing Suboxone clinics in Tennessee are granted a BeSMART certification. BeSMART certification occurs only when a clinic consistently performs with the highest level of compliance and patient care.
  • The Owners Are in Recovery
    No one understands opioid addiction like someone who has suffered through it personally. The owners at Nashville Addiction Clinic have done just that, and much more. After experiencing “less than great” Suboxone clinic appointments, they felt the need to provide a safe, friendly, professional atmosphere for people like them who suffer from opioid use disorder and are looking for high-quality treatment.
  • A Judgement-Free Suboxone Clinic
    When you have clinic owners who are in recovery for opioid addiction, you can bet the entire staff has a clear understanding of the common pitfalls that come with addiction. There’s no “three strikes rule” and relapse is treated with kindness and compassion, not ridicule. When a patient relapses they are simply given a higher level of care to help them correct their course and get back on track with their recovery.

Start a Telemedicine Suboxone Program Today - Accepting All Major Insurance and TennCare

Click a button below to register for treatment. Same-day appointments for new patients are available every Monday through Friday from 8:00 AM to 5:00 PM, and evenings until 9:00 PM every Monday and Wednesday. TennCare Medicaid and all major insurance plans are accepted.